Previous sepsis finding reversed in death of six-year-old

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The six-year-old girl who died of sepsis was actually suffering from a rare blood condition triggered by E.coli infection, an investigation has found.

Coco Rose Bradford died on 31 July 2017 at the Bristol Royal Hospital for Children, having been transferred three days earlier from the Royal Cornwall Hospital, then known as Treliske Hospital.

His death was the subject of an independent review published in autumn 2018, which found that opportunities for sepsis treatment were missed and critical to the care provided by staff at Treliske.

In particular, doctors were criticized for failing to deliver antibiotics as quickly as possible.

The Royal Cornwall Hospitals Trust also apologized to Koko’s family for failing to recognize and treat sepsis.

Coco Bradford died of a rare blood condition (Bradford Family/PA) , bp mean

But on Friday, Dr Andrew Cox, the coroner sitting at Truro, found that Koko had died of multiple organ failure due to hemolytic uremic syndrome (HUS).

This condition is caused by toxins released from an E.coli infection and sees the destruction of red blood cells after platelets form clots in small blood vessels.

It primarily affects the kidneys, but can also affect other organs, including the brain – especially in children – causing confusion and, in some cases, seizures.

HUS can cause tissue death in the brain, which can result in serious brain damage.

There is no proven treatment for HUS, but antibiotics are not recommended because they can cause E.coli to release its toxins, which can worsen the disease.

I think Coco had a tremendous husband, didn’t have massive sepsis

Over the course of eight days of investigation, it emerged that a microbiology report searching for “massive sepsis/husband” had been taken out of context.

In his conclusion on Friday, Mr Cox commented that none of the other tests indicated that Koko had a diagnosis of sepsis.

He said it was “deeply regrettable” that the family had been misled for the past four years, adding: “Indeed, I think Coco had severe sepsis, but heavy husband.”

Coco did not die of sepsis, a coroner found (Bradford Family/PA) , bp mean

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